Heterodox
Not all genes, their mutations, and the conditions caused by those mutations are overwhelmingly complex. We’ve known for decades that sickle cell disease is caused by a specific nucleotide change at a specific position in the human adult beta globin gene, and we can predict the consequences to a patient with the disease to a high degree of accuracy. The fact that there are so many CRISPR trials underway now is testament to the clarity of our...
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