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Tag Archives: self-amplifying mRNA vaccine

Next generation mRNA vaccines

In 2020, I was a subject in the Moderna phase III trial for their COVID mRNA vaccine. At the same time, Pfizer-BioNTec trialed a similar mRNA vaccine. Both mRNA vaccines proved highly successful. In both cases, chemically modified mRNA encoding the SARS-CoV-2 spike protein is injected, programming cells that receive the mRNA to produce and secrete spike protein until the mRNA decays.Now, a innovative self-amplifying mRNA vaccine has been approved in...

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