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New German study shows kids with corona may be as infectious as adults

Summary:
New German study shows kids with corona may be as infectious as adults Combined data from both PCR instruments show that viral loads of at least 250,000 copies, a threshold we previously established for the isolation of infectious virus in cell culture at more than 5% probability, were present across the study period in 29.0% of kindergarten-aged patients 0-6 years old (n=38), 37.3% of those aged 0-19 (n=150), and in 51.4% of those aged 20 and above (n=3153). The differences in these fractions may also be due to differences in test utilization. We conclude that a considerable percentage of infected people in all age groups, including those who are pre- or mild-symptomatic, carry viral loads likely to represent infectivity. Based on these results and

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New German study shows kids with corona may be as infectious as adults

New German study shows kids with corona may be as infectious as adultsCombined data from both PCR instruments show that viral loads of at least 250,000 copies, a threshold we previously established for the isolation of infectious virus in cell culture at more than 5% probability, were present across the study period in 29.0% of kindergarten-aged patients 0-6 years old (n=38), 37.3% of those aged 0-19 (n=150), and in 51.4% of those aged 20 and above (n=3153). The differences in these fractions may also be due to differences in test utilization. We conclude that a considerable percentage of infected people in all age groups, including those who are pre- or mild-symptomatic, carry viral loads likely to represent infectivity. Based on these results and uncertainty about the remaining incidence, we recommend caution and careful monitoring during gradual lifting of non-pharmaceutical interventions. In particular, there is little evidence from the present study to support suggestions that children may not be as infectious as adults …

The viral loads observed in the present study, combined with earlier findings of similar attack rate between children and adults (2​–​​5)​, suggest that transmission potential in schools and kindergartens should be evaluated using the same assumptions of infectivity as for adults. There are reasons to argue against the notion of adult-like infectivity in children, such as the fact that asymptomatic children are less likely to spread the virus by coughing, and have smaller exhaled air volume than adults. However, there are other arguments that speak in favour of increased transmission probability, such as the greater physical activity and closer social engagement of children.

Christian Drosten et al.

Lars Pålsson Syll
Professor at Malmö University. Primary research interest - the philosophy, history and methodology of economics.

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