Tag Archives: Hot Topics

I don’t know what to do about the widespread complete ignorance about the concepts of null hypothesis, rejection, failure to reject, p-levels. I will rant after the jump A glossary is urgently needed. 1. Size — the size of the test is the probability that a true null hypothesis will be rejected. For purely historical reasons the size 0.05 is often discussed. This is basically because the smallest 95% interval of a normal is roughly an even 4 standard...

A Very Grey Swan Keynes and Knight famously simultaneously in 1921 identified the concept of fundamental uncertainty as a situation not understandable by using a probability distribution, an idea popularized by Nassim Taleb just as the 2008 crash happened as a “black swan.”  Taleb defined white swans as situations describable by Gaussian normal distributions.  For situations not full uncertainty or white swans Taleb coined the idea of “grey swans,”...

There is a severe Remdesivir shortage On March 2 2020, I warned you that this was going to happen. I did not warn about the opaque and arbitrary Trump administration policy, because the Trump administration is always “worse than you imagine possible even taking into account the fact that it is worse than you imagine possible” Brad DeLong 2003 or so referring to the last Republican presidency. When are Americans going to notice the pattern ?...

It looks like many states are preparing to end stay at home quarantine. If you look at the numerous charts around on the number of new  coronavirus-19 cases reported each day it looks encouraging.  They show a peaking and a very slow decline or at best a  plateau. However, this plateau is the product of two very different curves for New York city and the rest of the country.  It is New York city falling and the rest of the country rising significantly....

SCOTUS decided 8-1 in favor of health insurance companies and coops in MAINE COMMUNITY HEALTH OPTIONS v. UNITED STATES decision, April 27, 2020 to be paid. I have been following this issue since 2015 and SCOTUS finally ruled on Republican’s (Sessions, Upton, Kingston) blockage of the Risk Corridor Program funding. A bit of history to explain how we got to this point. Letter to the editor at Modern Healthcare Alert (2019): “If you are going to report on...

I have repeatedly argued that, based on in vitro evidence, hydroxychloroquine should be prescribed while we wait for the results of clinical trials. Such results were just published. They are very disappointing. The link is to an LA Times Article: latimes.com 2020-04-17 malaria-drugs-fails-to-help-coronavirus-patients-in-controlled-studies On the other handEarly peek at data on Gilead coronavirus drug suggests patients are responding to treatment The...

[embedded content]James Smith protesting the protestors who are practicing unsafe methods of protest. They congregate in close proximity to others, failed to wear facemasks, threatened those people who were involved in the protest, and by their actions purposely prevented people and healthcare workers from having access to Sparrrow hospital in Lansing, Michigan. Their right to protest shall not impede upon the rights of others to safety....

by Dale Coberly A BEAR STORY FOR JASON WITH HOPE [Jason is a “Libertarian”  who recently tortured his brain to produce a proof that we have no obligation to help anyone else, because they are probably bad or will sometime, if given the chance, do something bad.] A long time ago I saw a film clip.  I don’t know who shot it or how. A hero, but not the hero of this story.  The film opens on a mountainside where a bear has found a dead elk, or killed it...

In the last two weeks of March and the first week of April, 2020 16.5 million new claims for unemployment were filed in the U.S. After the novel coronavirus is successfully contained some but not all of those jobs will return. The post-pandemic economy will not be the same as the economy before and to assume a return to business-as-usual economic growth would be folly. There will need to be immediate share-the-work policies along with basic income...

This is interesting. In addition to the two huge multi center phase III trials of Remdesivir for Covid 19 with estimated completion some time in May 2020, there is a smaller but very large trial in Beijing with estimated completion May 1 2020. The East is Remd ! May Day May Day May Day “Estimated Study Completion Date : May 1, 2020” Finally there is a very large trial in Hubei province with estimation completion date April 27 2020 “Estimated Study...