A follow-up to the much longer report on Insulin (test on this later) and how PBMs impact pricing on other drugs. “Insulin A Drug Pricing Analysis,” Angry Bear. “Drug manufacturers alone set and raise drug prices, and PBMs are holding drug companies accountable by negotiating the lowest possible cost for drugs, including insulins, on behalf of patients.“ According to 46brooklyn, this is an overly simplistic view on drug pricing. It should be...
Read More »Buprenorphine IV: What about Cocaine and Methamphetamine?
I have been thinking about buprenorphine, naltrexone and the stimulants cocaine and methamphetamine. An issue which came to my mind recently and which I think it worth discussing is that cocaine is often cut and replaced with fentanyl to hide the over-dilution. This is sometimes done sloppily leading to fentanyl overdoses of people who did not know they were consuming opiates. This is another reason to provide naltrexone to all who request...
Read More »Public funding for bringing transformative drugs to market
AB: It is a government policy to turn the fruits of its research over to private industry without any strings attached. The 1980 Bayh-Dole Act allows the National Institutes of Health (NIH) and universities housing government-funded scientists to patent and transfer (for royalties, of course) their scientific discoveries, research tools, and drug candidates to private developers. Smaller entities are created to do the research and development of new...
Read More »Opioids in America
In 2019 the age-adjusted death rate from an opioid overdose was 21.6 per 100,000 people. This compares with 12.9 for kidney disease, 14.2 from suicides, 14.7 for influenza, 21.6 from diabetes, and 161.5 from heart disease (the leading cause of death in the United States). Opioid overdose deaths place in the top 10 leading causes of death in the United States. As can been from Figure 1, prior to 2015 most of these opioid deaths arose from prescription (Rx) overdoses, but after that they came...
Read More »Homicides Over Time, Plus a Question About Drugs
I was looking for information on drug related murders and inadvertently stumbled on this old Bureau of Justice of Statistics report. There’s a lot of interesting information in it. One fascinating table is this: For context, here is the population breakdown over a period that includes the timespan in the table. I’m not sure this gives enough information to say what would happen if drugs were legalized, but I am interested in your thoughts....
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