Europe’s Response to Coronavirus and the Implications for the U.S. As I listened to the morning news about the coronavirus crisis, I was reminded of this critique of the Eurozone: In a recent conference, the distinguished economist Paul Krugman repeated the oft-heard critique that the eurozone is not an optimal currency area. Waltraud Schelkle disagrees with this characterisation, and argues that no country or group of countries represents an optimal...
Read More »Benefit-Cost Analysis and the Coronavirus
Benefit-Cost Analysis and the Coronavirus We are in the middle of a flurry of decision-making on how to deal with COVID-19. After much resistance, officials are now canceling public events, closing schools and discouraging other activities that put us in contact with each other. Travel restrictions and possible shutdowns of workplaces, as we’ve seen in Italy, may be up next. It’s interesting we haven’t heard anything about benefit-cost analysis in...
Read More »Three related metrics of coronavirus
Three related metrics of coronavirus Here are three different but ultimately related updates about the coronavirus pandemic. 1. It is 100x more lethal than the 2009 H1N1 swine flu The latest right-wing disinformation is that Obama waited 6 months to declare the 2009 swine flu an emergency, and 1000 people died. As others have pointed out, his Secretary of Health and Human Services did so only 11 days into the US outbreak. So why don’t we remember a big...
Read More »Coronavirus update: reason for alarm; (small) reason for hope
Coronavirus update: reason for alarm; (small) reason for hope This weekend has continued the discouraging news: reports just about everywhere that the Young Invulnerables packed the bars Friday night; the Petri dishes of airport security lines packed with Americans returning from Europe; and personally, two friends who I have known for almost 40 years getting very sick this past week and not able to be tested for coronavirus (one of whom by the way went...
Read More »Coronavirus Treatment Case Report
“First Case of 2019 Novel Coronavirus in the United States” Holshue et al 2020 I quote Treatment with intravenous remdesivir (a novel nucleotide analogue prodrug in development10,11) was initiated on the evening of day 7, and no adverse events were observed in association with the infusion. Vancomycin was discontinued on the evening of day 7, and cefepime was discontinued on the following day, after serial negative procalcitonin levels and negative nasal...
Read More »LIfe in Rome
I am in a city with a curfew (enforced ?) where only pharmacies, supermarkets and those stores where someone from China sells all sorts of household stuff are open. Rome hasn’t reached the dread levels of Wuhan and Milan, but the Italian government is trying to get ahead of the curve. It is strange and alarming that there is little traffic (it is also impressive that Romans don’t obey the traffic code even when there is little traffic). People are really...
Read More »Turn Up the Humidity in Your House
This is coming from MEDPAGE TODAY, “Track the U.S. COVID-19 Outbreak in Real Time,” Comments Section (3 comments), March 11, 2020 with regard to COVID-19 “The mechanism of seasonal effect for seasonal respiratory virus spread is believed to be humidity, not temperature. In New York state which has 220 cases, fomites lose moisture where indoor humidity is low, allowing the lighter particles to stay longer in the aerosol. In Florida and Arizona, with 38...
Read More »A Sunday reflection
The BSing of the Red Death: and a K.I.S.S. model for the coronavirus pandemic A Reuters/Ipsos poll this past week found that only 2 in 10 Republicans, vs. 4 in 10 Democrats, say the coronavirus poses an imminent threat to the United States. In keeping with that lack of concern, fewer republicans are taking any steps to prepare, such as washing their hands more frequently. Anecdotally, from several GOPers in my neighborhood as well as from the proverbial...
Read More »Novel Coronavirus and Better Unsafe than Sorry
It is possible that a known pharmaceutical called remdesivir inhibits the reproduction of the Covid-19 coronavirus. It inhibits (some) RNA dependendent RNA Polymerases — the type of enzyme the virus uses to replicated its genome and express its genes. It is known that it is a potent inhibitor of the RNA dependendent RNA Polymerases used by the MERS coronavirus update: here is a good site for Covid-19 data. So what will be done with remdesivir ? What...
Read More »Medicare Could Use the VA’s Negotiation Results on Insulins and Other Drugs
VA-Like Negotiations on Insulin Prices Could Save Medicare Billions, MedPage Today, Zeena Nackerdien, February 21, 2020 I am going to dispense with the reasoning dissing the increased pricing of Insulin and go straight to a pricing strategy. Suffice it to say, the various versions developed of Insulin do not justify the pricing increases seen today. Recently, Philip Longman (“Best Care Anywhere”) was advocating for Medicare pricing for everyone using...
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