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Tag Archives: Healthcare

From Social Distance to Social Justice: An Unsolved Riddle

In the last two weeks of March and the first week of April, 2020 16.5 million new claims for unemployment were filed in the U.S. After the novel coronavirus is successfully contained some but not all of those jobs will return. The post-pandemic economy will not be the same as the economy before and to assume a return to business-as-usual economic growth would be folly. There will need to be immediate share-the-work policies along with basic income...

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Remdesivir V

This is interesting. In addition to the two huge multi center phase III trials of Remdesivir for Covid 19 with estimated completion some time in May 2020, there is a smaller but very large trial in Beijing with estimated completion May 1 2020. The East is Remd ! May Day May Day May Day “Estimated Study Completion Date : May 1, 2020” Finally there is a very large trial in Hubei province with estimation completion date April 27 2020 “Estimated Study...

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Experts and Me… An op-ed by Robert Waldmann

(Dan here..Robert leads with a disclaimer, but I respectfully disagree it does not belong here. So this is lifed from Robert’s Stochastic Thoughts). Experts and Me This is much too self indulgent for Angry Bear. I am trying to understand what I think of the recent discussion of leaving things up to the experts. Donald Trump is making a very convincing case for leaving things up to experts by pretending to be able to outguess them using his gut. I remain...

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The FDA

I am back complaining about the FDA as I have in The Ethics of Clinical Trials and 10 years earlier Clinical Trial Ethics (an aside — I had forgotten the old post and Google reminded me that I have been banging this drum for a decade). Now I have a lot of company, because of the pandemic. Many people (including the ex FDA director Gottlieb retweeted by a Senator Brian Schatz) argue that the extreme circumstances imply that delays that are normally...

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Remdesivir IV

This post is not up to the standards of the New England Journal of Medicine Compassionate Use of Remdesivir for Patients with Severe Covid-19 is an important article written and published with amazing speed. The (many) authors (including professional writers) assess the experience of 53 “patients who received remdesivir during the period from January 25, 2020, through March 7, 2020, and have clinical data for at least 1 subsequent day.” I think I’m just...

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Abbreviated Coronavirus dashboard for April 12: fundamentally, still flying blind

Abbreviated Coronavirus dashboard for April 12: fundamentally, still flying blind Here is the update through yesterday (April 11) This is an abbreviated version, covering just the essentials. Number and rate of increase of Reported Infections (from Johns Hopkins via arcgis.com) Number: up +28,391 to 530,006 (vs. 35,219 prior peak on April 10) Figure 1 ***Rate of increase: day/day: 6% (vs. 8% for the past week, and 8% on April 9) Yesterday marked the...

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Why was the PREDICT Program Suspended Last Fall?

Why was the PREDICT Program Suspended Last Fall? A discussion from October 29, 2019: A crucial federal program tracking dangerous diseases is shutting down. Predict, a pandemic preparedness program, thrived under Bush and Obama. Now it’s canceled … Ever since the 2005 H5N1 bird flu scare, the US Agency for International Development (USAID) has run a project to track and research these diseases, called Predict. At a cost of $207 million during its...

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Coronavirus dashboard for April 11: new high in daily infections as testing falls further behind

Coronavirus dashboard for April 11: new high in daily infections as testing falls further behind Here is the update through yesterday (April 10) I’ve changed the format, moving the “just the facts, ma’am” data to the top, and comments to the end. Significant new developments are indicated in italics. The four most important metrics are starred (***) below. Number and rate of increase of Reported Infections (from Johns Hopkins via arcgis.com)  Number:...

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Remdesivir and Transfer Pricing III

Remdesivir and Transfer Pricing III Robert Waldmann posted his Remdesivir III: I do not understand the need for “evidence-based medicine” or rather I do not understand how the phrase is used by doctors. There is no evidence that Covid 19 patients (without heart disease) do better without Chloroquine. I learn that “evidence based medicine” does not imply choosing the therapy that a fair balance of evidence suggests is best for the patient. Pharmaceuticals...

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