A clinical trial of hydroxychloroquine with 30 patients (15 treated 15 controls) has been completed in Shanghai. It is the first genuine randomized trial. It reports no evidence that hydroxychloroquine works at all. It is true, that given the principal outcome measure defined in advance, the trial has no power. Not low power, 0 power. In a hypothetical, if all patients treated with hydroxychloroquine became healthy immediately with no symptoms and no...
Read More »It is Clear that Hydroxychloroquine and Chloroquine are Currently Used to Treat Covid 19 in the USA
Patient privacy prevents precise calculation of the fraction of Covid 19 patients in the USA being treated with Hydroxychloroquine or Chloroquine. However, Hospitals are purchasing hugely increased amounts Christopher Rowland reports. Data gathered in the first 17 days of March by Premier Inc., a large group purchasing organization for 4,000 U.S. hospitals, showed a 300 percent week-over-week increase in orders of chloroquine and a 70 percent...
Read More »Hydroxychloroquine, Anthony Fauci and Kevin Drum
This is a comment on “Is Anthony Fauci Really Our Truthteller-in-Chief?” by Kevin Drum. I will briefly summarize. Drum quotes from the latest press conference “Is there any evidence to suggest that, as with malaria, it might be used as a prophylaxis against COVID-19? DR. FAUCI: No. The answer is no.” later after Trump says hydroxychloroquine is the cure for Covid 19 Fauci changed his line to Q I would like Dr. Fauci, if you don’t mind, to follow up on...
Read More »The best US solution to the coronavirus pandemic: SHUT.IT.DOWN — two weeks of China + one month of South Korea
The best US solution to the coronavirus pandemic: SHUT.IT.DOWN — two weeks of China + one month of South Korea For the last few weeks, I have been screaming at the top of my lungs about “exponential growth.” That’s because so few people realized the impact such growth could have in a pandemic, over the course of just a few months, even weeks.I first began thinking about this as soon as I read a Tweet by Trevor Bedford a month ago about how coronavirus...
Read More »What do we want ? Hydroxychloroquine (update without Azithromycin) and Remdesivir. When do we want it ? Now
I will never forgive Donald Trump for saying something exceedingly controversial with which I agree. I hate to say this but I agree with Trump and disagree with Fauci on hydroxychloroquine and Remdesivir. Update: But don’t mix the Hydroxychloroquine with Azithromycin“Azithromycin: (Major) Avoid coadministration of hydroxychloroquine and azithromycin.” Thanks Ted Lieu I will discuss hydroxychloroquine here because there is no legal issue. It can be...
Read More »A Rehash, Stimuli Considered, And ACA Healthcare Insurance Assistance
I am sure by now many of you have read what the gov is and is not doing for us. The later is more prevalent as can be witnessed in the stimuli being offered. I am going to ask you to pay attention to the last item on ACA Healthcare Insurance. Whether you qualified or not in the past, you may be eligible for assistance now. I have broken this out into 4-points of which many of us might find ourselves. If you questions, PLEASE ASK, I will try to answer. The...
Read More »Moscow Mitch was hoping the fever would break
[embedded content]The closing remarks of Moscow Mitch McConnell statement before the vote to spare Donald John Trump his presidency. He was talking about “factional fever” that the “framers” referred to as a concern for majorities acting in a partisan manor. And yet, here we are.
Read More »Bailouts
Given the Coronavirus crisis, there will be bailouts. Should there be bailouts ? If so how should firms be bailed out ? I think it is useful to look at the last round of bailouts from 2008-9 for lessons learned. First with the benefit of hindsight, does it seem that bailing out firms was a mistake ? On the one hand one can argue that it was necessary to prevent the Great Depression. It is hard to discuss whether it was worth the cost, because there...
Read More »Let’s get real about coronavirus testing . . .
We do not know how severe the covid-19 epidemic will be or how much economic and social pain it will cause, but it clearly has the potential to kill hundreds of thousands or even millions of Americans, and the economic consequences could include a deep recession and even a financial crisis that will cause misery to tens of millions of people. Testing is key to getting the epidemic under control, and it is not clear to me that policymakers are being nearly...
Read More »Remdesivir II
This is, in fact, another post on Coronavirus, but it will take me a while to get to the point. To put the conclusion here, I think that it is important to get the FDA out of the way (by executive order if necessary). The Food and Drug Act, as currently interpreted, requires the assumption that people should (generally) not be treated with pharmaceuticals which haven’t been proven to be safe and effective. The rule is first do no harm, second do no harm....
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