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The Angry Bear

Remdesivir IV

This post is not up to the standards of the New England Journal of Medicine Compassionate Use of Remdesivir for Patients with Severe Covid-19 is an important article written and published with amazing speed. The (many) authors (including professional writers) assess the experience of 53 “patients who received remdesivir during the period from January 25, 2020, through March 7, 2020, and have clinical data for at least 1 subsequent day.” I think I’m just...

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Can the House Democrats drive a hard bargain on CARES 2?

Michael Grunwald argues in Politico that House Democrats have a lot of bargaining power in negotiations over the next coronavirus relief bill, but that they are not aggressively using their leverage.  He suggests that Democrats are holding back because they are worried about being labeled obstructionist and getting blamed if legislation does not pass. I agree with some of his analysis and have doubts about other parts.  But here I want to make a...

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Abbreviated Coronavirus dashboard for April 12: fundamentally, still flying blind

Abbreviated Coronavirus dashboard for April 12: fundamentally, still flying blind Here is the update through yesterday (April 11) This is an abbreviated version, covering just the essentials. Number and rate of increase of Reported Infections (from Johns Hopkins via arcgis.com) Number: up +28,391 to 530,006 (vs. 35,219 prior peak on April 10) Figure 1 ***Rate of increase: day/day: 6% (vs. 8% for the past week, and 8% on April 9) Yesterday marked the...

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CNN’s Slavish Service to Trump

CNN’s Slavish Service to Trump I had to do a double-take when I saw this news item.  First came the headline, “Pence won’t let public health officials appear on CNN unless Trump’s disinfo briefings run in full”.  I thought, this is horrible: the administration is holding Fauci and Birx hostage to force CNN to cover not only them but also Trump in his daily blatherings.  But no, it was exactly the other way around.  Pence was keeping them from being...

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Why was the PREDICT Program Suspended Last Fall?

Why was the PREDICT Program Suspended Last Fall? A discussion from October 29, 2019: A crucial federal program tracking dangerous diseases is shutting down. Predict, a pandemic preparedness program, thrived under Bush and Obama. Now it’s canceled … Ever since the 2005 H5N1 bird flu scare, the US Agency for International Development (USAID) has run a project to track and research these diseases, called Predict. At a cost of $207 million during its...

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Something Good From The Panemic? Maybe A Cease Fire In Yemen

Something Good From The Panemic? Maybe A Cease Fire In Yemen Yes, in the midst of deaths and deep recession there may be someting good that may come from this pandemic.  Saudi Arabia’s leaders have announced a cease fire in Yemen after five years of war, one also accepted by its ally, the recognized government there.  Unfortunately so far the Houthi enemies of the Saudis and the recognized government have not so far accepted this proposed cease fire,...

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Coronavirus dashboard for April 11: new high in daily infections as testing falls further behind

Coronavirus dashboard for April 11: new high in daily infections as testing falls further behind Here is the update through yesterday (April 10) I’ve changed the format, moving the “just the facts, ma’am” data to the top, and comments to the end. Significant new developments are indicated in italics. The four most important metrics are starred (***) below. Number and rate of increase of Reported Infections (from Johns Hopkins via arcgis.com)  Number:...

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Remdesivir and Transfer Pricing III

Remdesivir and Transfer Pricing III Robert Waldmann posted his Remdesivir III: I do not understand the need for “evidence-based medicine” or rather I do not understand how the phrase is used by doctors. There is no evidence that Covid 19 patients (without heart disease) do better without Chloroquine. I learn that “evidence based medicine” does not imply choosing the therapy that a fair balance of evidence suggests is best for the patient. Pharmaceuticals...

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Lessons from the Pandemic

Lessons from the Pandemic First, all who produce things we need or want are “essential workers”.  Health care practitioners are essential, but so are the people who stock pharmacies and grocery and hardware stores or staff customer service phone lines.  Truck drivers are essential.  Farmworkers who pick the crops we plan on eating are too.  Nothing demonstrates whose work matters in this world better than a pandemic that threatens to pull them off the...

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